IL-22 antibody
Rabbit anti Human Interleukin-22
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- IL-22
Rabbit anti Human Interleukin-22 antibody specifically recognizes human interleukin-22 (IL-22), a regulatory cytokine and member of the IL-10 family, secreted by activated T cells, which signals through a class II cytokine receptor system consisting of IL-22R and IL-10R-beta/CRF2-4. IL-22 has been shown to act as an inhibitor of the production of IL-4 by Th2 cells, up-regulate the production of acute phase reactants in the pancreas and liver, and to be up-regulated in intestinal inflammation associated with Crohn’s disease. |
- Target Species
- Human
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
N.B. For functional studies do not add sodium azide - Antiserum Preparation
- Antiserum to human IL-22 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- Recombinant human IL-22
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml after reconstitution
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 0.5 | 2.0ug/ml | |
Functional Assays | 1.0 | 2.0ug/ml | |
Western Blotting | 0.1 | 0.2ug/ml |
- ELISA
- This purified human IL-22 antibody may be used in an indirect ELISA with recombinant human IL-22 (PHP209) as the standard.
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- Synonyms
- IL-TIF
- RRID
- AB_2264692
- UniProt
- Q9GZX6
- Entrez Gene
- IL22
- GO Terms
- GO:0006953 acute-phase response
- GO:0005125 cytokine activity
- GO:0005615 extracellular space
- GO:0007267 cell-cell signaling
- GO:0045518 interleukin-22 receptor binding
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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