IL-1 Beta Antibody (PrecisionAbTM Antibody) | 1A7

IL-1 Beta Antibody (PrecisionAb<sup>TM</sup> Antibody) | 1A7 gallery image 1

Western blot analysis of whole cell lysates probed with IL-1 Beta antibody followed by detection with Goat anti Mouse HRP conjugated (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 18 second exposure. Arrow points to IL-1 Beta (molecular weight 31 kDa)

  • IL-1 Beta Antibody (PrecisionAb<sup>TM</sup> Antibody) | 1A7 thumbnail image 1
  • Mouse anti Interleukin-1 beta
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    Interleukin-1 beta antibody recognizes interleukin-1 beta, also known as catabolin, pre-interleukin 1 beta or pro-interleukin-1-beta.
    • Product Type
      PrecisionAb™ Monoclonal
    • Isotype
    • Format
      Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
      VMA00633WBdatasheet pdfdatasheet pdf100 µl
      Secondary Antibodies
      Negative Isotype Controls
      Useful Reagents
      Positive Controls
      Histology Controls
      • Mouse anti Human interleukin-1 beta antibody recognizes interleukin-1 beta, also known as catabolin, pre-interleukin 1 beta and pro-interleukin-1-beta.

        The protein encoded by IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (provided by RefSeq, Jul 2008).

        Mouse anti Human interleukin-1 beta antibody detects a band of 31 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
      • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
      • Application NameYesNoMin DilutionMax Dilution
        Western Blotting1/1000

      • PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
      • Copyright © 2017 Bio-Rad Antibodies (formerly AbD Serotec)

      Recommended Secondary Antibody

        DescriptionProduct CodePack SizeApplicationsList PriceQuantity
        Goat anti Mouse IgG (H/L):HRPSTAR207P2 mlWB

        Recommended Negative Isotype Control

          Useful Reagents

            Recommended Positive Controls

              Histology Controls

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