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Native Human IgG4 used as a standard for the development of a human IgG4 ELISA.
Anti-cE5 IgG1 and IgG4 responses.
(A) Box plots of anti-cE5 IgG1 and IgG4 levels among the 207 individuals of the Aug 1994 survey. Boxes, whiskers, dots and P value as in Figure 1. IgG1 and IgG4 levels are expressed in ng/ml. (B) Scatter plot reporting the IgG1 (red) and IgG4 (black) antibody response to cE5 as function of age (n?=?207). The best-fit lines (solid) and 95% CI (broken lines) are shown. Note that three data points are outside the axis limits.
From: Rizzo C, Lombardo F, Ronca R, Mangano V, Sirima SB, Nèbiè I, Fiorentino G, Modiano D, Arcà B.
Differential antibody response to the Anopheles gambiae gSG6 and cE5 salivary proteins in individuals naturally exposed to bites of malaria vectors.
Parasit Vectors. 2014 Nov 28;7:549.