HOXA11 Antibody | 8B8

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HOXA11 Antibody | 8B8 gallery image 1

Staining of paraffin-embedded human endometrium with Mouse anti Human HOXA11 (MCA4918Z)

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  • HOXA11 Antibody | 8B8 thumbnail image 1
  • Mouse anti Human HOXA11:Preservative Free
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    8B8
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA4918ZP, WBdatasheet pdfdatasheet pdf0.1 mg
    MCA4918Z
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Mouse anti Human HOXA11 antibody, clone 8B8 recognizes human Homeobox protein Hox-A11, also known as HOXA11 or Homeobox protein Hox-1I. HOXA11 is a 313 amino acid ~35 kDa sequence specific transcription factor, part of a developmental regulatory system.

      Mutation of the HOXA11 gene can lead to the development of Radioulnar synostosis with amegakaryocytic thrombocytopenia (RSAT) a syndrome with bone marrow failure and skeletal deformities presenting with proximal fusion of the radius and ulna, resulting in extremely limited pronation and supination of the forearm (Thompson & Nguyen 1990).
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein A
    • Preservative Stabilisers
      None present
    • Immunogen
      Recombinant protein corresponding to aa 60-167 of human HOXA11
    • Purity
    • Approx. Protein Concentrations
      Ig concentration 0.5 mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
    • Fusion Partners
      Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
    • Storage
      Store at -20oC only.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      sequence-specific DNA binding
      transcription regulator activity
      sequence-specific DNA binding transcription factor activity
      regulation of transcription, DNA-dependent
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunohistology - Paraffin0.110 ug/ml
      Western Blotting0.110 ug/ml

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional HOXA11 Antibody Formats

    Formats Clone Applications Sizes available
    HOXA11 Antibody : Preservative Free 8B8 P, WB 0.1 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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