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High Mobility Group Protein B2 antibody | 3E5

Mouse anti Human High Mobility Group Protein B2:Preservative Free

Product Type
Monoclonal Antibody
Clone
3E5
Isotype
IgG2a
Specificity
High Mobility Group Protein B2

Product Code Applications Pack Size List Price Your Price Qty
MCA4792Z
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IF P WB 0.1 mg loader
List Price Your Price
loader

Mouse anti Human High Mobility Group Protein B2 antibody, clone 3E5 recognizes human high mobility group protein B2, also known as HMGPB2 or HMG-2. Human high mobility group protein B2 is a 208 amino acid ~22 kDa multifunctional protein with roles in chromatin remodeling and posesses antimicrobial properties.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Immunogen
Recombinant protein corresponding to aa 1-196 of human Human High Mobility Group Protein B2.
Approx. Protein Concentrations
Ig concentration 0.5 mg/ml
Fusion Partners
Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence 0.1 10 ug/ml
Immunohistology - Paraffin 0.1 10 ug/ml
Western Blotting 0.1 10 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Description Rabbit F(ab')2 anti Mouse IgG:FITC

RRID
AB_2117906
UniProt
P26583
Entrez Gene
HMGB2
GO Terms
GO:0000793 condensed chromosome
GO:0001938 positive regulation of endothelial cell proliferation
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0006334 nucleosome assembly
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006265 DNA topological change
GO:0006288 base-excision repair, DNA ligation
GO:0006309 DNA fragmentation involved in apoptotic nuclear change
GO:0008301 DNA bending activity
GO:0010843 promoter binding
GO:0016563 transcription activator activity
GO:0016565 general transcriptional repressor activity
GO:0048015 phosphatidylinositol-mediated signaling
GO:0032075 positive regulation of nuclease activity
GO:0033151 V(D)J recombination
GO:0042056 chemoattractant activity
GO:0043234 protein complex
GO:0043388 positive regulation of DNA binding
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0050786 RAGE receptor binding
GO:0060326 cell chemotaxis
GO:0071222 cellular response to lipopolysaccharide
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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