Focal Adhesion Kinase Antibody

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Staining of formalin fixed, paraffin embedded human ductal and lobular epithelium with Rabbit anti Human focal adhesion kinase (AHP1106)

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  • Rabbit anti Human Focal Adhesion Kinase
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP1106P *datasheet pdfdatasheet pdf50 µg
    AHP1106
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Rabbit anti Human Focal Adhesion Kinase antibody recognizes human focal adhesion kinase 1, also known as Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71 or Protein-tyrosine kinase 2. Focal adhesion kniase belongs to the Tyr protein kinase family and contains a single FERM domain and a single protein kinase domain. Rabbit anti Human Focal Adhesion Kinase antibody detects an epitope within the internal region of Focal adhesion kinase (FAK), a 125kD cytoplasmic protein tyrosine kinase that is activated by numerous stimuli and controls cell motility, proliferation and apoptosis. FAK resides at focal adhesions that form between cells growing in the presence of extracellular matrix constituents (Brami-Cherrier et al. 2014).FAK is a highly conserved molecule amongst vertebrate species and the immunogen sequence domonstrates 100% identity with mouse, rat, many non-human primates, bovine, rabbit and chicken species.

      FAK plays a potential role in oncogenic transformation, and its expression is thought to be correlated to tumour invasiveness (Ibbetson et al. 2013).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunohistology - Paraffin(1)25ug/ml
      (1)
      This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
      Ductal and lobular epithelium.
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Focal Adhesion Kinase Antibody Formats

    Formats Applications Sizes available
    Focal Adhesion Kinase Antibody : Purified P * 50 µg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      DescriptionProduct CodePack SizeApplicationsList PriceQuantity
      Goat anti Rabbit IgG (Fc):BiotinSTAR121B1 mgE, WB
      STAR121B
      Sheep anti Rabbit IgG:Biotin2AB02B1 mlC, E, P, WB
      2AB02B
      Sheep anti Rabbit IgG:DyLight®488STAR36D488GA0.1 mgF, IF
      STAR36D488GA
      Sheep anti Rabbit IgG:DyLight®549STAR36D549GA0.1 mgF, IF
      STAR36D549GA
      Sheep anti Rabbit IgG:DyLight®649STAR36D649GA0.1 mgF, IF
      STAR36D649GA
      Sheep anti Rabbit IgG:Dylight®800STAR36D800GA0.1 mgF, IF, WB
      STAR36D800GA
      Goat anti Rabbit IgG (Fc):FITCSTAR121F1 mgF
      STAR121F
      Sheep anti Rabbit IgG:FITCSTAR34B1 mgC, F
      STAR34B
      Goat anti Rabbit IgG (Fc):HRPSTAR121P1 mgE, WB
      STAR121P
      Goat anti Rabbit IgG (H/L):HRPSTAR124P1 mgC, E, WB
      STAR124P
      Sheep anti Rabbit IgG:HRP (Multi Adsorbed)STAR541 mgC, E, WB
      STAR54
      Sheep anti Rabbit IgG:RPESTAR35A1 mlF
      STAR35A

      Recommended Negative Isotype Control

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          Antigen Retrieval Buffer, pH8.0BUF025C50 mlP
          BUF025C
          Antigen Retrieval Buffer, pH8.0BUF025A500 mlP
          BUF025A

          Recommended Positive Controls

            Histology Controls

              Ductal and lobular epithelium.

              References

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