Factor VII Antibody | RFF-VII/1

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Factor VII Antibody | RFF-VII/1 gallery image 1

Human factor VII detected in human serum with Mouse anti Human factor VII (MCA4681)

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  • Factor VII Antibody | RFF-VII/1 thumbnail image 1
  • Mouse anti Human Factor VII
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    RFF-VII/1
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA4681E, R, WB*datasheet pdfdatasheet pdf0.5 mg
    MCA4681
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Mouse anti Human Factor VII antibody, clone RFF-VII/1 recognizes Factor VII, a serine protease found circulating in the blood. It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor. Tissue factor is found on the outside of blood vessels. When the vessels is damaged, tissue factor is exposed to the blood and circulating Factor VII. Once bound to tissue factor, Factor VII is activated by different proteases and converts Factor IX to IXa. Factor VII deficiency is a rare hereditary haemorrhagic disease. Symptoms range from mild to severe.

      Clone RFF-VII/1 is a strong inhibitor of Factor VII activity. It may be used to detect Factor VII in immunoassays in combination with clone RFF-VII/2 as a capture reagent.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA1/201/200
      Radioimmunoassays
      Western Blotting(1)
      (1)
      MCA4680 binds to a conformational epitope and will not bind to reduced Factor VII.

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Factor VII Antibody Formats

    Formats Clone Applications Sizes available
    Factor VII Antibody : Purified RFF-VII/1 E, R, WB* 0.5 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

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          Recommended Positive Controls

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              References

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