CTNS Antibody | 5G6

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CTNS Antibody | 5G6 gallery image 1

Western blot analysis of CTNS expression in HepG2 using Mouse anti Human CTNS:Azide Free (MCA4010Z)

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  • CTNS Antibody | 5G6 thumbnail image 1
  • Mouse anti Human CTNS:Preservative Free
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    5G6
  • Isotype
    IgG2a
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA4010ZWBdatasheet pdfdatasheet pdf0.1 mg
    MCA4010Z
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Human CTNS antibody, clone 5G6 recognizes human cystinosin, also known as CTNS. CTNS is a 367 amino acid ~ 55 kDa multi-pass lysozomal transmembrane glycoprotein acting to transport cystine from the lysozome. Two isoforms of cystinosin may be generated by alternative splicing, Mouse anti Human CTNS antibody, clone 5G6 is expected to recognize both described isoforms (Uniprot: O60931).

      Defects in the CTNS gene can lead to the inherited lysozomal storage disease cystinosis (Kalatzis et al. 2001)
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein A
    • Preservative Stabilisers
      None present
    • Immunogen
      Recombinant protein corresponding to aa 1 - 101 of human CTNS.
    • Purity
    • Approx. Protein Concentrations
      Ig concentration 0.5 mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
    • Fusion Partners
      Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
    • Storage
      Store at -20oC only.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      integral to membrane
      glutathione metabolic process
      lysosomal membrane
      L-cystine transmembrane transporter activity
      ATP metabolic process
      cognition
      late endosome
      brain development
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting0.110 ug/ml

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional CTNS Antibody Formats

    Formats Clone Applications Sizes available
    CTNS Antibody : Preservative Free 5G6 WB 0.1 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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