Ceruloplasmin Antibody

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  • Sheep anti Human Ceruloplasmin
  • Sheep anti Human Ceruloplasmin:HRP
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
2 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    1940-0004C, Edatasheet pdfdatasheet pdf1 ml
    1940-0004
    1940-0004PC, Edatasheet pdfdatasheet pdf1 ml
    1940-0004P
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Sheep anti Human ceruloplasmin antibody detects ceruloplasmin, a ~132kDa metalloprotein that is secreted into the plasma by liver hepatocytes and activated monocytes/macrophages. Ceruloplasmin functions in copper transport, iron homeostasis, antioxidant defence, angiogenesis and coagulation.

      Deficiency in ceruloplasmin is termed aceruloplasminemia, an autosomal recessive disorder which leads to iron accumulation and tissue damage, in particular in the brain and visceral organs. Clinical features include retinal degeneration, diabetes mellitus and neurological disturbances.

      Elevated plasma ceruloplasmin has been shown to pose an increased risk in atherosclerosis and myocardial infarction.
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified IgG - liquid
      Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography
      Purified IgG prepared by affinity chromatography on Protein G
    • Preservative Stabilisers
      0.09% Sodium Azide (NaN3)
      0.01% Thiomersal
      HRP Stabiliser (BUF052A)
    • Immunogen
      Highly pure human ceruloplasmin
    • Purity
    • Approx. Protein Concentrations
      IgG concentration 5.0 mg/ml
      Ig concentration 1.0 mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
      Phosphate buffered saline
    • Storage
      Store at +4oC or at -20oC if preferred.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted.
      Avoid repeated freezing and thawing as this may denature the antibody.
      Should this product contain a precipitate we recommend microcentrifugation before use.
      Store at +4oC. DO NOT FREEZE.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
      18 months from date of despatch.
    • GO Terms
      transmembrane transport
      ferroxidase activity
      oxidation-reduction process
      extracellular space
      chaperone binding
      copper ion transport
      cellular iron ion homeostasis
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA
      Immunohistology - Frozen
    • Application NameYesNoMin DilutionMax Dilution
      ELISA1/1001/5000
      Immunohistology - Frozen1/101/500

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

    • Technical Advice
    • Technical Advice
    • Recommended Protocol
    • Recommended Protocol
    • ELISA
      This antibody has been used at dilutions as high as 1/400K in a simple ELISA with 0.1 µg of antigen coated per well.
    • ELISA
      This antibody has been used at dilutions as high as 1/400K in a simple ELISA with 0.1 µg of antigen coated per well.
    • Immunohistology
    • Immunohistology
    • Histology Positive Control Tissue
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Immunofluorescence
    • Western Blotting
    • Western Blotting
    • Instructions For Use
    • Instructions For Use

    Additional Ceruloplasmin Antibody Formats

    Formats Applications Sizes available
    Ceruloplasmin Antibody : Purified C, E 1 ml
    Ceruloplasmin Antibody : HRP C, E 1 ml
    • Copyright © 2016 Bio-Rad

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      Donkey anti Sheep/Goat IgG:DyLight®488STAR88D488GA0.1 mgF, IF
      STAR88D488GA
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      STAR88D549GA
      Donkey anti Sheep/Goat IgG:DyLight®649STAR88D649GA0.1 mgF, IF
      STAR88D649GA
      Donkey anti Sheep/Goat IgG:FITCSTAR88F1 mgC
      STAR88F
      Donkey anti Sheep/Goat IgG:HRPSTAR88P1 mlC, E, P, WB
      STAR88P

      Recommended Negative Isotype Control

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          TMB Signal+BUF054A100 mlE
          BUF054A
          TMB CoreBUF056A100 mlE
          BUF056A
          TMB Core PrestainedBUF057A100 mlE
          BUF057A
          TMB Core+BUF062A100 mlE
          BUF062A

          Recommended Positive Controls

            Histology Controls

              References

              Further Reading

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