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CD61 Antibody

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Staining of formalin fixed, paraffin embedded human placenta with Rabbit anti Human CD61 (AHP1227)

  • CD61 Antibody thumbnail image 1
  • Rabbit anti Human CD61 (N-Terminal)
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP1227P *datasheet pdfdatasheet pdf50 µg
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    • Rabbit anti human CD61 (N-terminal) antibody detects an epitope within the N-terminal region of human CD61, also known as integrin beta 3 (ITGB3). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. CD61 is a 90-110 kDa glycoprotein which binds to CD41 (ITGA2B) to form the GPIIb/IIIa complex, and CD51 (ITGAV) to form the vitronectin receptor.

      Binding of fibrinogen to the GPIIb/IIIa complex brings about platelet/platelet interaction, leading to rapid platelet aggregation and clotting. The vitronectin receptor is essential for endothelial cell migration, proliferation, and prevention of apoptosis.

      Elevated expression of the vitronectin receptor is associated with tumour progression and metastases formation on melanoma cells, and is used by human cytomegalovirus (HCMV) as a co-receptor to initiate viral entry and signalling.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunohistology - Paraffin(1)1020ug/ml
      This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
      Placenta, terminal villi, red blood cells.
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional CD61 Antibody Formats

    Formats Applications Sizes available
    CD61 Antibody : Purified P * 50 µg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      DescriptionProduct CodePack SizeApplicationsList PriceQuantity
      Goat anti Rabbit IgG (Fc):BiotinSTAR121B1 mgE, WB
      Sheep anti Rabbit IgG:Biotin2AB02B1 mlC, E, P, WB
      Sheep anti Rabbit IgG:DyLight®488STAR36D488GA0.1 mgF, IF
      Sheep anti Rabbit IgG:DyLight®549STAR36D549GA0.1 mgF, IF
      Sheep anti Rabbit IgG:DyLight®649STAR36D649GA0.1 mgF, IF
      Sheep anti Rabbit IgG:Dylight®800STAR36D800GA0.1 mgF, IF, WB
      Goat anti Rabbit IgG (Fc):FITCSTAR121F1 mgF
      Sheep anti Rabbit IgG:FITCSTAR34B1 mgC, F
      Goat anti Rabbit IgG (Fc):HRPSTAR121P1 mgE, WB
      Goat anti Rabbit IgG (H/L):HRPSTAR124P1 mgC, E, WB
      Sheep anti Rabbit IgG:HRP (Multi Adsorbed)STAR541 mgC, E, WB
      Sheep anti Rabbit IgG:RPESTAR35A1 mlF

      Recommended Negative Isotype Control

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          Antigen Retrieval Buffer, pH8.0BUF025C50 mlP
          Histar Detection SystemSTAR3000B150 TestsC, P
          Histar Detection SystemSTAR3000A50 TestsC, P
          Histar Detection SystemSTAR3000C500 TestsC, P
          Antigen Retrieval Buffer, pH8.0BUF025A500 mlP

          Recommended Positive Controls

            Histology Controls

              Placenta, terminal villi, red blood cells.
                • Product Images

                • CD61 Antibody thumbnail image 1


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