Goat anti Human CD192 antibody recognizes an epitope within the N-terminal (NT) region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4.
Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1.
Purified IgG - liquid
Antiserum to human CD192 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
0.1% Sodium Azide (NaN3) 0.1% Bovine Serum Albumin
Synthetic peptide C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-terminal region of human CD192.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml
Reagents In The Kit
Preparing The Antibody
Phosphate buffered saline.
Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
This product is suitable for use in indirect ELISA applications.