Catenin Beta Antibody | 1C9

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Catenin Beta Antibody | 1C9 gallery image 1

Western blot analysis of A431 squamous carcinoma whole cell lysate probed with Mouse anti Human catenin beta-1 antibody (MCA4879Z) followed by HRP conjugated Goat anti Mouse IgG, visualized by chemiluminescence

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  • Catenin Beta Antibody | 1C9 thumbnail image 1
  • Mouse anti Human Catenin Beta:Preservative Free
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    1C9
  • Isotype
    IgG2a
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA4879ZWBdatasheet pdfdatasheet pdf0.1 mg
    MCA4879Z
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Mouse anti Human catenin beta antibody, clone 1C9 recognizes human catenin beta, a 780 amino acid ~95 kDa downstream component of the Wnt signaling pathway.

      Two isoforms of catenin beta produced by alternative splicing have been described. Mouse anti Human catenin beta antibody, clone 1C9 binds to the canonical isoform 1. Clone 1C9 is not expected to bind to the truncated isoform 2 which lacks the immunogen sequence used to generate the antibody (UniProt : P35222).

      Catenin beta has been implicated in the pathogenesis of Colorectal cancer (CRC), being associated with the progression from the premalignant adenoma to the invasive adenocarcinoma (Morin et al. 1997). Catenin beta has also been implicated in the pathogenesis of Pilomatrixoma (PTR), a common benign skin tumor with the appearance of cutaneous circumscribed ‘buttons’ usually in the head and neck area, attached to the overlying skin and to the subcutaneous matrix (Chan et al. 1999).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting0.110 ug/ml

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Catenin Beta Antibody Formats

    Formats Clone Applications Sizes available
    Catenin Beta Antibody : Preservative Free 1C9 WB 0.1 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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