Sheep anti Human C3c antibody recognizes the C3c component of human complement, formed as a result of the inactivation of C3b. Sheep anti Human C3c antibody may be used for the detection of C3 deposits in tissues following complement activation.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
1. Kennedy, M.W. & Kuo, Y.M. (1988) The surfaces of the parasitic nematodes Trichinella spiralis and Toxocara canis differ in the binding of post-C3 components of human complement by the alternative pathway.Parasite Immunol. 10:459-63.
2. Oyeyinka, G.O. et al. (2003) The effects of ageing on the immune response to Schistosoma haematobium and hookworm by measuring circulating immune complexes, C3, IgG, IgA and IgM levels in residents of Omi dam area of Kogi State, Nigeria.Afr J Med Med Sci. 32: 263-7.
3. Rojana-Udomsart, A. et al. (2013) Complement-mediated muscle cell lysis: A possible mechanism of myonecrosis in anti-SRP associated necrotizing myopathy (ASANM).J Neuroimmunol. 264: 65-70.