C1q

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  • Native Human C1q
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Antigen
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    2221-5504Edatasheet pdfdatasheet pdf1 mg
    2221-5504
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Native Human Complement Component C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis.
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified C1q from human serum - lyophilised
    • Reconstitution
      Reconstitute with 1.0ml distilled water
      Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
      The solution may appear cloudy following reconstitution
    • Preparation
    • Preservative Stabilisers
      None present
    • Purity
      SDS PAGE: >96%
      Single band at 410kDa in PAGE.
    • Approx. Protein Concentrations
      Total protein concentration 1.0 mg/ml after reconstitution
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      0.01M Na2EDTA
      0.3M NaCl, pH 7.5
    • Storage
      Store at +4oC. DO NOT FREEZE.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      3 months from date of reconstitution.
    • GO Terms
      innate immune response
      cell-cell signaling
      complement component C1 complex
      negative regulation of granulocyte differentiation
      negative regulation of macrophage differentiation
      extracellular region
      complement activation, classical pathway
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional C1q Formats

    Formats Applications Sizes available
    C1q : Purified E 1 mg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              • Application NameReference Images
                ELISA

              References

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