BACE1 Antibody

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Goat anti Human Bace1 antibody used for the detection of BACE1 in neurons on formalin fixed, paraffin embedded hippocampus sections from a patient with Alzheimer's disease

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  • Goat anti Human BACE1 (C-Terminal)
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP740P *datasheet pdfdatasheet pdf0.1 ml
    AHP740
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
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    References
    Reviews
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    • Goat anti BACE1 antibody recognizes human beta-site APP-cleaving enzyme 1, also known as beta- secretase 1, BACE1, Aspartyl protease 2, Asp2 or Memapsin-2. BACE1 is a 501 amino acid, the aminio terminal 45 residues constituting the signal and propeptide moieties, ~70 kDa aspartic protease.

      BACE1 is involved in the cleavage of the amyloid precursor protein (APP) leading to the generation and extracellular release of soluble amyloid beta peptide (Lin et al. 2000). Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease (Vassar et al. 1999).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunohistology - Paraffin(1)1/1001/200
      (1)
      This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional BACE1 Antibody Formats

    Formats Applications Sizes available
    BACE1 Antibody : Serum P * 0.1 ml
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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