Annexin I (ANXA1), otherwise known as Lipocortin 1, is a calcium-dependent phospholipid-binding protein and member of the annexin family, preferentially expressed on the cytosolic face of the plasma membrane, which acts as an inhibitor of phospholipase A2, and may exhibit anti-inflammatory activity. Increased expression of the ANXA1 gene in hairy cell leukaemia, can be used in immunohistochemistry as a highly-sensitive diagnostic marker.
Purified recombinant protein - liquid
Purified recombinant 6xHis-tagged ANXA1 expressed in E.coli
Approx. Protein Concentrations
Total protein concentration 0.2mg/ml
41.4kD (368 amino acid residues with tag)
Reagents In The Kit
Preparing The Antibody
Phosphate buffered saline
Store at -70oC. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.