Bio-Rad Antibodies entity map

“For over six decades, Bio-Rad Laboratories has served life science research and clinical diagnostics customers worldwide through its global network of operations.”

About Bio-Rad-Antibodies - published by Bio-Rad Antibodies

“In January 2013, Bio-Rad acquired AbD Serotec, a world leading antibody manufacturer and supplier with over 35 years' experience in the antibody market. In May 2016, AbD Serotec fully transitioned into the Bio-Rad brand, changing its name from AbD Serotec, a Bio-Rad company to Bio-Rad.”

About Bio-Rad-Antibodies - published by Bio-Rad Antibodies

“Bio-Rad’s innovative StarBright™ Dyes have been specifically designed to fit seamlessly into your multicolor panels. Their exceptional brightness, narrow excitation and emission characteristics, and compatibility with different buffers help you effortlessly address common assay challenges and build bigger, better panels with ease. Discover the vast range of StarBright Dyes across each laser line or explore our collection of resources created to support you in getting the most out of your experiments.”

StarBright Dyes for Flow Cytometry - published by Bio-Rad Antibodies

“Our antibody range also includes the highly validated Precision Ab™ antibodies for western blotting.”

All Antibody, Kits & Reagent Products - published by Bio-Rad Antibodies

“At Bio-Rad, we are committed to providing our customers with reliable research tools and are constantly raising our standards for antibody quality. The PrecisionAb Antibody range, rigorously tested in western blotting for specificity and reproducibility, is designed to help researchers produce the highest-quality western blotting data.”

PrecisionAbs - Validated Antibodies for Western Blotting - published by Bio-Rad Antibodies

“We understand that design and optimization of immunoassays is complex and time consuming. Having an antibody in only one format limits your options, and the resulting assay may not answer all your questions. Producing several different conjugates or alternative formats can be tedious and costly, and delay your progress.”

TrailBlazer Antibodies - published by Bio-Rad Antibodies

“We have incorporated SpyTag-SpyCatcher technology into our custom HuCAL® recombinant antibody generation service, to make TrailBlazer Antibodies. The service provides you with an extensive antibody toolbox that enables rapid development of robust assays, leading to results that advance your research.”

TrailBlazer Antibodies - published by Bio-Rad Antibodies

“Tailored to your specific needs, our team of specialists accelerates and simplifies your journey to identify functional biologics for your target of interest. A dedicated team of experienced scientists and technical specialists is assigned to each project, delivering a customized service designed to each client’s specifications and success criteria.”

Pioneer - Rapid Therapeutic Antibody Discovery Platform - published by Bio-Rad Antibodies

“The Pioneer™ Antibody Discovery Platform is designed to swiftly generate diverse, high-affinity therapeutic leads with strong developability profiles. At the core of this platform are Bio-Rad’s cutting-edge technologies: SpyDisplay and SpyLock. Together, they serve as powerful backup solutions to ensure a seamless, tailored workflow for antibody discovery, with project-specific validation provided by Bio-Rad’s expert team.”

Cutting-Edge Antibody Discovery Technologies - Pioneer Platform - published by Bio-Rad Antibodies

“We deliver a bespoke service of antibody discovery for each client based on their unique requirements. From challenging targets to pH sensitive antibodies and bispecifics, we can help you to accelerate your drug candidate discovery.”

Pioneer - Rapid Therapeutic Antibody Discovery Platform - published by Bio-Rad Antibodies

“Pioneer™ Select is a custom antibody generation service that delivers high-specificity recombinant antibodies using advanced phage display technology and rapid screening workflows. Built on a 220-billion-sequence library and Bio-Rad’s proprietary SpyDisplay selection technology, Pioneer Select enables rapid turnaround and flexible engagement models. Each antibody is precisely formatted and labeled via TrailBlazer™ technology to support PK and ADA assays, diagnostic immunoassays, basic research, and QC release testing in Fab, IgG, and additional formats.”

Pioneer Select - published by Bio-Rad Antibodies

“Bio-Rad's custom antibody generation service uses antibody phage display technology to create highly specific, high-affinity recombinant monoclonal antibodies for research, bioanalytical, and diagnostic use—with no animal immunization. When the specialized antibody you need is not commercially available, our HuCAL® and Pioneer™ Select platforms deliver purified, sequenced antibodies in as little as 4 weeks.”

Custom Recombinant Monoclonal Antibody Generation - published by Bio-Rad Antibodies

“Production of catalog antibodies in large quantity (bulk)”

Antibodies & Antigens for Research and Diagnostic Assay Development - published by Bio-Rad Antibodies

“Bio-Rad offers two options for the generation of large quantities of the antibodies in our catalog, either on a one-off basis or as part of a long-term arrangement: Option 1. Antibodies made to the same specification as stated in the catalog. Option 2. Antibodies that would have an alternative specification such as a change in the concentration or buffer.”

Quote Request for Bulk or Customised Catalog Antibodie - published by Bio-Rad Antibodies

“In vitro antibody production from a hybridoma cell line takes time, specialized equipment, and skills. Working with our experts for small to medium scale in vitro production of your antibody will enable you to make better use of your time and resources, improve your planning, and increase confidence in the final product.”

In Vitro Antibody Production Service - published by Bio-Rad Antibodies

“Building multicolor flow cytometry panels can be a daunting process as it can be complex and time consuming. There are many considerations to take into account such as the instrument configuration, the most suitable antibody, the biology of the cells, and with so many fluorescent dyes to choose from, including new StarBright™ Dyes, this can be confusing.”

Free Customized Flow Cytometry Panel Building Service - published by Bio-Rad Antibodies

“We are continually looking to expand the range of antibodies and other reagents that we offer to researchers around the world. If you have any reagents that you would like us to consider for licensing we would be very keen to hear from you - our licensing procedures are simple and flexible, and often provide researchers and departments with valuable additional income.”

License Your Antibody - published by Bio-Rad Antibodies

“At Bio-Rad, we pride ourselves on the quality of Technical & Customer Service that we provide to our customers. Each regional office is staffed with experienced scientists trained to answer your questions on all our products. We believe that providing high-quality products and services are the key to customer satisfaction. In support of this goal, we are committed to providing a response in 24 hours or less.”

Technical Support, FAQs & Licence Queries - published by Bio-Rad Antibodies

“Science advances when we learn together. That’s why we created Bio-Rad Academy—a place where researchers can learn, connect, and expand their skills through engaging, expert-led online courses.”

Bio-Rad Academy | Free Online Life Science Courses - published by Bio-Rad Antibodies

“Bio-Rad offers over 11,000 antibodies and reagents for applications such as flow cytometry, immunofluorescence, and western blotting.”

All Antibody, Kits & Reagent Products - published by Bio-Rad Antibodies

“Primary antibodies exhibit high specificity and affinity for their target antigens. These may be monoclonal antibodies, which recognize and bind to only one specific epitope on a target antigen, or polyclonal antibodies, which are a mixture of immunoglobulin molecules capable of binding to multiple epitopes on the same antigen. Primary antibodies are mainly used in immunoassays such as ELISA, western blotting, immunohistochemistry, ChIP, and flow cytometry. They can be conjugated to enzymes or fluorophores for accurate detection and quantification of antigens.”

Monoclonal & Polyclonal Antibodies - published by Bio-Rad Antibodies

“Secondary antibodies recognize an antibody as their target antigen, usually referred to as the primary antibody which in turn is bound to its antigen or protein of interest.”

Secondary Antibodies - published by Bio-Rad Antibodies

“Bio-Rad offers the largest range of species-specific veterinary antibodies for immune analysis. The portfolio has been especially developed for enhancing the antibody and conjugate choice for multicolor flow cytometry. However, due to the paucity of veterinary antibody development there are gaps in the global portfolio. One way to overcome that is to use antibodies that have been shown to be cross-reactive based on peer reviewed publications and experimental data.”

Cross-Reactive Antibodies - published by Bio-Rad Antibodies

“When one antibody binds to an idiotope of another antibody it is referred to as an anti-idiotypic antibody. The variable part of an antibody including the unique antigen binding site is known as the idiotype. The combination of epitopes within the idiotype (i.e. the idiotopes) is unique for each antibody, figure 1.”

Anti-Idiotypic Antibodies - published by Bio-Rad Antibodies

“We offer over 350 antibodies against marketed biologic drugs suitable for pharmacokinetic (PK) and anti-drug-antibody (ADA) assays, to support bioanalytical assays for preclinical research and clinical trials, and therapeutic drug monitoring, for innovator and biosimilar products.”

Antibodies for Bioanalysis & Drug Monitoring - published by Bio-Rad Antibodies

“The increasing need to maximize data from a single sample has led to the development of fluorescent based multiplexing assays. Multiplex fluorescent western blotting enables the simultaneous analysis of multiple proteins in a single sample on the same blot, obtaining as much information as possible in one experiment.”

Multiplex Fluorescent Western Blotting - published by Bio-Rad Antibodies

“A matched antibody pair for ELISA consists of a capture antibody and a detection antibody. In a matched ELISA pair, each antibody is specific for a different and non-overlapping region or epitope of the antigen. By design, matched pairs function in a sandwich ELISA set-up; for further information on sandwich ELISA, guides and protocols go to the main ELISA page. Figure 1 below shows the sandwich ELISA protocol.”

Matched Antibody Pairs for ELISA - published by Bio-Rad Antibodies

“Isotype controls are a type of negative control designed to measure the level of non-specific background signal caused by primary antibodies, based upon the tissue type of the sample. Usually, the background signal is the result of immunoglobulins binding non-specifically to Fc receptors present on the cell surface. For example, antibodies raised in mice, particularly those of the IgG2a isotype, will bind strongly to some human leukocytes regardless of the test antibody specificity. In this case you would need a mouse IgG2a isotype control for use with human cells or tissues.”

Isotype Controls - Negative Isotype Controls - published by Bio-Rad Antibodies

“As specialists in the flow cytometry field, our antibody portfolio includes an extensive selection of primary antibodies tested in flow cytometry, including our new StarBright Dye conjugated antibodies. Feel free to filter the table below, using our target species button or the individual filters within the table, to find exactly what you are looking for.”

Flow Cytometry Antibodies - published by Bio-Rad Antibodies

“Most immunoassays including ELISA, immunohistochemistry, western blot and flow cytometry rely on reagents for experimental success. These reagents include wash buffers, blocking solutions, assay diluents, and substrate buffers, all of which are crucial for accurate and consistent results.”

Buffers & Reagents - published by Bio-Rad Antibodies

“Fully human antibody controls and calibrators as an alternative to sourcing positive control sera”

Antibodies & Antigens for Research and Diagnostic Assay Development - published by Bio-Rad Antibodies

“The ZE5 Cell Analyzer is an innovative flow cytometer with flexible configurations to meet a broad range of experimental complexities and throughput needs – accessible for novice flow cytometry users yet flexible enough for the most experienced flow cytometry professionals.”

ZE5 Cell Analyzer - published by Bio-Rad Antibodies

“The S3e Cell Sorter is enhanced with the AutoGimbal System, which enables hands-free motorized nozzle tip alignment. Real-time automation allows walk-away cell sorting.”

S3e Cell Sorter - published by Bio-Rad Antibodies

“The ZOE Cell Imager simplifies fluorescence microscopy with an intuitive touch-screen interface to control the brightfield, three fluorescence channels, and integrated digital camera.”

ZOE Fluorescent Cell Imaging System - published by Bio-Rad Antibodies

“The TC20 Automated Cell Counter can quickly and accurately count cells in suspension. It can be used with or without trypan blue for viable cell or total cell counts on a broad range of cell types and sizes. Counting can be performed significantly faster than manual methods whilst improving reproducibility.”

TC20 Automated Cell Counter - published by Bio-Rad Antibodies

“Bio-Rad’s new spectraviewer is the only spectraviewer to allow a multi-laser view and support 3 applications in a single tool.”

Fluorescence Spectraviewer - published by Bio-Rad Antibodies

“The ability to select antigen density and fluorophores based on brightness, combined with automatic exclusion of incompatible fluorophores, will help you build larger panels with confidence.”

Multicolor Flow Cytometry Panel Builder - published by Bio-Rad Antibodies

“Planning a flow cytometry experiment can often be a time-consuming activity with many different aspects to consider. Our Flow Cytometry Design Tool streamlines this process by providing you with all the information you need, including protocols, resources, and products, specifically tailored to your experiment plus a customizable Experiment Planner.”

Flow Cytometry Design Tool - published by Bio-Rad Antibodies

“Click the identifiers within the images below to discover the antibodies that Bio-Rad provides to these markers.”

Phenotype Finder - published by Bio-Rad Antibodies

“Choose a cell type or use the search bar to easily match markers to specific immune cells and find antibodies for your chosen markers.”

Human Immune Cell Markers - Selection Tool - published by Bio-Rad Antibodies

“Choose a cell type or use the search bar to easily match markers to specific immune cells and find antibodies for your chosen markers.”

Mouse Immune Cell Markers - Selection Tool - published by Bio-Rad Antibodies

“Using the knowledge from the “Experimental design – how-to reference guide” section and your desired application, follow the steps below to discover your ideal secondary antibody.”

Secondary Antibody Selection Process - Step by Step - published by Bio-Rad Antibodies

“Traditional western blot workflows can require significant hands-on time for gel and membrane staining, transfer verification, blocking, and housekeeping protein normalization. Bio-Rad's Western Blot Time Savings Calculator shows how much time you could reclaim with the Stain-Free western blot workflow.”

Western Blot Time Savings Calculator - Compare Laboratory Workflow Efficiency - published by Bio-Rad Antibodies

“Bio-Rad exclusively offers two online calculators for generating colorimetric and fluorometric readings with alamarBlue. Your raw data can be converted into quantitative results and exported to Excel with a few clicks. Our how to use alamarBlue page uses example protocols for your reference.”

Colorimetric & Fluorometric Calculators - published by Bio-Rad Antibodies

“Bio-Rad believes that finding the right antibody for your experiments should be as easy as possible. You shouldn’t need to scroll through multiple pages to determine whether an antibody is suitable for your desired application, or comes in the required format.”

Find an Antibody with A.I.den - published by Bio-Rad Antibodies

“The innovative SpyTag and SpyCatcher technology, also termed 'molecular superglue', has been employed by the scientific community in many ways to build proteins with novel properties, and address the challenges of detecting and controlling proteins. We have added SpyTag to our recombinant Fab antibodies and produced a set of SpyCatchers to 'glue' to the Fab to make TrailBlazer Antibodies.”

SpyTag & SpyCatcher Products - published by Bio-Rad Antibodies

“Flow cytometry is a powerful technique used in a wide range of research areas. However, producing robust results is not always easy. That’s why Bio-Rad is with you across the entire flow cytometry journey. With over 40 years of experience, we can help you plan smarter, generate high-quality data, and analyze results with confidence. From intuitive tools and trusted reagents to expert advice and best-in-class guidance, we’re with you at every stage.”

Flow Cytometry Essentials - published by Bio-Rad Antibodies

“Western blotting, also known as immunoblotting or protein blotting, is a core technique in cell and molecular biology. In most basic terms, it is used to detect the presence of a specific protein in a complex mixture extracted from cells or tissue.”

Western Blot - What is Western Blotting? - published by Bio-Rad Antibodies

“Enzyme-linked immunosorbent assays (ELISAs) are the most common immunoassay type and used to detect the presence and measure the amount/concentration of specific analytes (e.g. antibodies) in a sample. In diagnostics, ELISAs are frequently used to determine whether and how many antibodies have been produced in response to pathogen exposure or vaccination.”

ELISA - Antibodies, Kits, Reagents for highly sensitive assays - published by Bio-Rad Antibodies

“Immunohistochemistry (IHC) experiments are used to visualize antigens/proteins in a tissue with the help of enzymatically or fluorescently labeled antibodies. The technique is commonly applied in the clinic and in academic research to distinguish healthy from morphologically abnormal tissue. Depending on how the tissue has been prepared, the IHC technique is referred to as IHC-paraffin, IHC-frozen or IHC-free floating.”

Immunohistochemistry - IHC Antibodies, Kits & Reagents - published by Bio-Rad Antibodies

“In an immunofluorescence (IF) experiment a primary antibody binds specifically to a protein of interest present in a sample (e.g. fixed cells, tissue sections). The antibody binding is then visualized by a fluorescent detection system (hence the name immunofluorescence), which provides information about the localization of the protein.”

Immunofluorescence - Antibodies, Kits, Protocols & Tips - published by Bio-Rad Antibodies

“In an immunoprecipitation (IP) experiment, an antibody is cross-linked to agarose, sepharose or magnetic beads in order to capture a protein of interest present in a lysate. The technique is mainly used for the analysis of protein-protein interactions, the characterization of protein complexes and the identification of post-translational modifications.”

Immunoprecipitation - Products, Protocols, Tips & Tricks - published by Bio-Rad Antibodies

“Cancer is a complex multi-factorial disease; its development is triggered by a combination of genetic and environmental factors. Important hereditary factors include mutations in proto-oncogenes, tumor suppressor genes, and DNA damage repair components.”

Cancer Antibodies, Proteins, & Reagents for Research - published by Bio-Rad Antibodies

“Bio-Rad offers a comprehensive range of quality cell biology reagents, including many unique specificities, which cover key research areas such as apoptosis, cancer research, cell signaling, and cell morphology.”

Cell Biology Antibodies & Reagents - published by Bio-Rad Antibodies

“No experiment is complete without all the pieces and one key piece is confidence in the health of your cells. Determining the health of your cells is a crucial component to ensure the reproducibility of your experiments and it can even be the experimental result.”

Cell Health Antibodies, Kits & Dyes - published by Bio-Rad Antibodies

“Cell proliferation is the rapid expansion of a cell population due to cell growth and division. This cellular process has to be carefully regulated as the smallest alterations can result in an uncontrolled increase of cell numbers, and eventually cancer. To sustain homeostasis and ultimately prevent carcinogenesis, uncontrolled cell proliferation is often counteracted by an increase in apoptosis.”

Cell Proliferation and Viability Detection Reagents - published by Bio-Rad Antibodies

“Immunology is a broad and complex research area that encompasses innate immunity, adaptive immunity and immune regulation in the naive state and in response to infection and disease.”

Immunology Antibodies - Cell Surface Markers - published by Bio-Rad Antibodies

“Innate immunity is the front line, non-specific and immediate response to pathogens and to the unrecognized self. As a part of the larger immune system, innate immunity comprises a variety of molecules, cell types and signaling cascades which typically do not adapt to previous infection or vaccination.”

Innate Immunity Antibodies - published by Bio-Rad Antibodies

“Infectious disease research is based on multidisciplinary scientific and diagnostic development work and application workflows, incorporating techniques and knowledge from human medicine via translational model animals to veterinary pathologies.”

Infectious Disease Antibodies & Antigens - published by Bio-Rad Antibodies

“Bio-Rad is committed to providing you with the best neuroscience antibodies. With our ISO 9001 certified manufacturing facilities, you can depend on us for high quality products.”

Neuroscience Antibodies - published by Bio-Rad Antibodies

“The definition of cell death is the irreversible degeneration of cellular functions resulting in the loss of cellular integrity (Galluzzi et al. 2018). Cell death is a crucial step in organism development, tissue homeostasis, and host defense.”

Regulated Cell Death - published by Bio-Rad Antibodies

“Through a combination of in-house product development and collaboration with global leaders in veterinary research, Bio-Rad brings reagents to market that enable pure veterinary immune research, applied animal health investigation, and translational research for human disease models.”

Veterinary Antibodies - Translational Animal Model - published by Bio-Rad Antibodies

“Lab Crunches is Bio-Rad Antibodies’ expert blog covering antibody selection, validation, and experimental best practices across flow cytometry, western blotting, ELISA, immunohistochemistry, immunology research, and more.”

Lab Crunches - Antibody Blog - published by Bio-Rad Antibodies

“Keep your mind active during lab breaks, or warm-up for the day ahead on your commute, with short podcasts from Bio-Rad.”

Podcasts on Flow Cytometry, Cell Cycle & Antibodies - published by Bio-Rad Antibodies

“Poor reproducibility of results is a widespread issue in scientific research (Goodman 2018). A survey carried out by Nature in 2016 highlighted that greater than 70% of researchers have struggled to reproduce experiments carried out by another scientist, and many researchers have encountered issues reproducing their own data. Irreproducible data holds back scientific progress, as well as hampering individual research efforts (Baker 2016). It is imperative that observations can be repeated to establish biological truths, like interacting proteins and identification of cell types.”

Antibody Validation Principles - published by Bio-Rad Antibodies

“Bio-Rad has an ISO9001 certified antibody production facility in Kidlington, near Oxford, UK.”

About Bio-Rad-Antibodies - published by Bio-Rad Antibodies

“ISO 9001:2015 is an internationally recognized standard for quality management systems. Both our manufacturing sites in Kidlington, UK and Neuried, Germany are ISO 9001:2015 certified, which demonstrates our continued commitment to ensuring our products meet quality requirements and customer expectations.”

ISO 9001 Quality Assurance Management - published by Bio-Rad Antibodies

“Bio-Rad is committed to providing high-quality products and unrivaled technical support services to support its customers.”

Our Guarantees to You - published by Bio-Rad Antibodies

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Batch/Lot Specific Datasheets - published by Bio-Rad Antibodies