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IL-1 Beta antibody

Rabbit anti Dog Interleukin-1 beta

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IL-1 Beta

Product Code Applications Pack Size List Price Your Price Qty
AHP2980
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
List Price Your Price
loader

Rabbit anti Dog interleukin-1 beta antibody recognizes canine interleukin-1 beta (IL-1β), a 17.5 kDa pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. It is secreted by activated macrophages and monocytes and is involved in the modulation of a wide range of immune and inflammatory responses.

IL-1β and the closely related IL-1α, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a.

Target Species
Dog
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to canine interleukin-1 beta were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant canine interleukin-1 beta
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1ug/ml 5ug/ml
Western Blotting 0.1ug/ml 2ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
ELISA
This product may be used as a capture antibody in a sandwich ELISA together with AHP2980B as the detection reagent. Recombinant Dog interleukin-1 beta (PDP014 ) may be used as a standard.

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UniProt
Q28292
Entrez Gene
IL1B
GO Terms
GO:0001660 fever generation
GO:0005125 cytokine activity
GO:0005149 interleukin-1 receptor binding
GO:0005615 extracellular space
GO:0006955 immune response
GO:0008083 growth factor activity
GO:0051781 positive regulation of cell division

AHP2980

142809 156224 158029

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

View more products with IL-1 BETA specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Dog Products
Please note