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Goat anti Dog IgA antibody used for the measurement of serum IgA levels in dogs dogs with atopic dermatitis by ELISA.
Correlation between the phenotypes and obvious population structure was detected in the GSD population. The difference in IgA levels (pdiff = 1.1×10-5, based on Welsh two sample t-test) in CAD cases and CAD controls (Ntotal = 184, before removing CAD controls with low IgA levels) is presented with boxplots (A). The GSD population is visualised with an MDS-plot displaying the formation of two subpopulations (B) with the uneven distribution of CAD cases and CAD controls (C). The distribution of IgA levels across the subpopulations is visualized with violin plots (D). Panels B-D include all dogs after QC (n = 203) and the dotted lines on the violin plots (A and D) correspond to the respective median values.
From: Tengvall K, Kierczak M, Bergvall K, Olsson M, Frankowiack M, et al. (2013) Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis. PLoS Genet 9(5): e1003475.