Negative Isotype Controls
- 9400-0409G recognises ubiquitin, a 8.6kDa cytoplasmic and nuclear protein which is highly conserved across species.
Ubiquitin functions as a protein modifier which covalently attaches to lysines as either a monomer or as a lysine-linked polymer. Attachment as a Lys-48 polymer usually leads to the target protein undergoing proteolytic degradation. Attachment as a monomer does not result in degradation and may be linked to functions including maintenance of chromatin structure, regulation of gene expression, stress response and DNA repair.
Ubiquitin can be detected in both normal and diseased brain tissues including the neurofibrillary tangles of Alzheimers disease, Lewy bodies in Parkinsons disease and Pick bodies in Pick’s disease.
Purified IgG prepared by affinity chromatography on Protein G
0.09% Sodium Azide (NaN3)
Native ubiquitin from bovine erythrocytes
Approx. Protein Concentrations
IgG concentration 5.0mg/ml
Reagents In The Kit
Preparing The Antibody
Phosphate buffered saline
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
18 months from date of despatch.
For research purposes only
Additional Ubiquitin Antibody Formats
Recommended Secondary Antibody
Recommended Negative Isotype Control
Recommended Positive Controls