PI-3 Kinase p85 Subunit Alpha Antibody | U13

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  • Mouse anti PI-3 Kinase p85 Subunit Alpha
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  • Product Type
    Monoclonal Antibody
  • Clone
    U13
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA1168IP, WBdatasheet pdfdatasheet pdf2 ml
    MCA1168
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Mouse anti PI-3 Kinase p85 Subunit alpha antibody, clone U13 recognizes the SH3 domain of the p85 alpha subunit of bovine PI3 kinase, also known as Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha or PtdIns-3-kinase regulatory subunit p85-alpha. p85 α PI3 kinase is a 724 amino acid ~85kDa protein bearing a single Rho-GAP domain, two SH2 domains and a single N-terminal SH3 domain. Multiple isoforms of the protein can be generated by alternative splicing, mouse anti PI-3 Kinase p85 subunit alpha antibody, clone U13 recognizes only those isoforms containing the SH3 domain (isoforms 1 and 4) but not those lacking the domain (isoforms 2,3 and 5).

      Deficiencies in the expression of the PIK3R1 gene can lead to immunodeficiency Agammaglobulinemia 7, autosomal recessive, diue to the inhibition of B cell development (Conley et al. 2012) and the develpmental condition SHORT syndrome (Chudasama et al. 2013).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ImmunoprecipitationNeat
      Western Blotting1/200

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional PI-3 Kinase p85 Subunit Alpha Antibody Formats

    Formats Clone Applications Sizes available
    PI-3 Kinase p85 Subunit Alpha Antibody : S/N U13 IP, WB 2 ml
    • Copyright © 2016 Bio-Rad Antibodies (formerly AbD Serotec)

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              • Application NameReference Images
                Immunoprecipitation
                Western Blotting

              References

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