Welcome to our Blog

Th2A Cells — the Latest T Helper Cell Subset and its Role in Allergy
May 16, 2018
Th2A cells are a recently identified subset of T helper cells type 2 (Th2). This blog looks at the role of Th2A cells in allergy.
Getting the Dose Right
Kimberley Bryon-Dodd
May 14, 2018
Suffering from a chronic condition can mean constant treatment for an extended period of time. This blog discusses therapeutic drug monitoring and why it is used for conditions such as IBD to ensure that treatment remains safe and effective.
Inking the Immune System: How Macrophages Make Tattoos Last
Kimberley Bryon-Dodd
Apr 04, 2018
Baranska et al. (2018) identify macrophage dynamics as being key to tattoos lasting in their recent study. This blog examines the paper in more detail and why tattoos are so difficult to remove.
How to Get More Out of Your Multicolor Panels
Kimberley Bryon-Dodd
Mar 13, 2018
This blog post explains how to build better panels for flow cytometry through optimizing for antigen density, using a dump channel and including viability markers.
SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part Two
Feb 13, 2018
In the second part of our series on SUMOylation, we examine how key cell signaling proteins are regulated by SUMOylation, the effect of their aberrant SUMOylation on signaling pathways and the potential of SUMO inhibitors in cancer therapy.
SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part One
Feb 09, 2018
In the first part of our two-part series on SUMOylation we discuss the discovery of SUMO and the importance of SUMOylation in cell cycle regulation and cellular proliferation.
Why EGF R is an Attractive Target for Cancer Therapy
Kimberley Bryon-Dodd
Jan 15, 2018
Epidermal growth factor receptor (EGF R) is the most extensively studied receptor tyrosine kinase. In this blog we examine the history of EGF R, the EGF R family and its function along with how EGF R promotes cancer development.
The underlying reason beta cells fail to proliferate in “diabesity” uncovered
Aug 21, 2017
Diabesity refers to the link between obesity and type 2 diabetes. This blog post describes the latest scientific findings describing the mechanism behind the failure of beta cells to proliferate in patients with type 2 diabetes, which could lead to novel treatments for this disease.