Below are a list of 5 top scientists we believe belong on the antibody hall of fame for their work in developing the world of antibody science. Let us know in the comment section if there is someone else you feel belongs on our antibody hall of fame.
Also known as “the father of immunology”, in 1796 Jenner developed the world’s first vaccine. The vaccine was against smallpox which killed around 20% of the population at that time.
In 1900, Paul Ehrlich, an American biologist, hypothesized ‘the selective theory’ that antigens bind to specific antibody side chain receptors.
In the 1940's, Linus Pauling confirmed Ehrlich's theory and showed the interation between antibodies and antigens is based on chemical structure, now known as the 'lock and key' theory.
In 1975 Milstein, together with Georges Kohler, was able to produce monoclonal antibodies against known antigens, for which they received a Nobel Prize in 1984. This began the commercialisation of monoclonal antibodies in clinical diagnostics.
In 1988, Greg Winter developed technology that allowed the use of monoclonal antibodies in humans. This meant they could be used for therapeutic purposes as it helped to overcome difficulties with reactions caused by using mice hosted antibodies in humans.
Who would you nominate to go on our antibody hall of fame?