Synthetic S-Adenosyl-Homocysteine

Product Type

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0100-0025 is S-(5'-Adenosyl)-L-homocysteine, C14H20N6O5S, the product of enzymatic transmethyation reactions involving S-Adenosylmethionine (SAM).

S-Adenosyl-homocysteine (CAS number: 979-92-0) hydrolyzes in acid solution (0.1M HCl, 100°C, over 90 minutes) to form S-ribosylhomocysteine. It is not hydrolyzed in neutral alkaline solutions (stable in 0.1M NaOH at 25°C over 10 minutes), but oxidation is more rapid in alkaline solution. S-Adenosyl-homocysteine is slowly oxidized to the sulfoxide as a solid and in solution. It is protected from oxidation by thiodiglycol; neutral solutions containing thiodiglycol are stable for long periods at 25°C.

Target Species
Product Form
Synthetic protein - liquid
Buffer Solution
0.1 M HCl
Preservative Stabilisers
None present
>99% by TLC
Approx. Protein Concentrations
1.0 mg/ml
Protein Molecular Weight
For research purposes only
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.