C1q

Product Details
- Target Species
- Human
- Product Form
- Purified C1q from human serum - lyophilised
- Reconstitution
- Reconstitute with 1.0ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
The solution may appear cloudy following reconstitution - Buffer Solution
- 0.01M Na2EDTA
0.3M NaCl, pH 7.5 - Preservative Stabilisers
- None present
- Purity
- SDS PAGE: >96%
Single band at 410kDa in PAGE. - Approx. Protein Concentrations
- Total protein concentration 1.0 mg/ml after reconstitution
Storage Information
- Storage
- Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- Guaranteed until date of expiry. Please see product label.
More Information
- UniProt
- P02745
- P02747
- P02746
- Entrez Gene
- C1QA
- C1QB
- C1QC
- GO Terms
- GO:0005602 complement component C1 complex
- GO:0006958 complement activation, classical pathway
- GO:0007267 cell-cell signaling
- GO:0045087 innate immune response
- GO:0005576 extracellular region
- GO:0030853 negative regulation of granulocyte differentiation
- GO:0045650 negative regulation of macrophage differentiation
- Regulatory
- For research purposes only
Applications of C1q
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA |
Product Specific References
References for C1q
-
Wenderfer, S.E. et al. (2007) Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.
Arthritis Res Ther. 9: R114. -
Kanda, Y. et al. (2007) Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types.
Glycobiology. 17 (1): 104-18. -
Kao, D. et al. (2015) A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors
Cell Reports. 6 Dec [Epub ahead of print]
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