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Tetanus Toxin antibody

Goat anti Clostridium tetani Tetanus Toxin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Tetanus Toxin

Product Code Applications Pack Size List Price Your Price Qty
OBT0967
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Goat anti Clostridium tetani tetanus toxin antibody recognizes the tetanus toxin of Clostridium tetani, an opportunistic pathogen commonly found in soil and the intestinal tracts of some animals. Tetanus toxin is a potent neurotoxin produced following the germination of C. tetani spores in wounds. It blocks neurotransmission by binding irreversibly to receptors in the brain and spinal cord.

Target Species
Bacterial
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Immunogen
Purified tetanus toxin.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunoprecipitation
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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References for Tetanus Toxin antibody

  1. Umezaki, Y. et al. (2011) Blocking synaptic transmission with tetanus toxin light chain reveals modes of neurotransmission in the PDF-positive circadian clock neurons of Drosophila melanogaster.
    J Insect Physiol. 57 (9): 1290-9.

RRID
AB_618848
UniProt
P04958
GO Terms
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0006508 proteolysis
GO:0008270 zinc ion binding
GO:0009405 pathogenesis
GO:0050827 toxin receptor binding
GO:0051609 inhibition of neurotransmitter uptake

OBT0967

131014 159638

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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